Search results for "Liver metabolism"

showing 9 items of 9 documents

Exercise and Conjugated Linoleic Acid Supplementation Induce Changes in the Composition of Liver Fatty Acids

2019

Exercise and supplementation with conjugated linoleic acid (CLA) are used to reduce body weight and to improve health. Applied together, they may exert a synergistic effect. However, the effects of exercise and CLA supplementation on liver metabolism are poorly understood. The aim of this study was to examine the influence of exercise and CLA supplementation on fatty acids (FA) composition in mouse liver. We analyzed 44 of known FAs of this organ by gas chromatography-mass spectrometry. Our results demonstrated that exercise contributed to a decrease in odd-chain FA and an increase in n-6 polyunsaturated FA contents. In turn, CLA stimulated an increase in branched-chain FAs and n-3 polyunsa…

0301 basic medicinemedicine.medical_specialtyPhysiologyConjugated linoleic acid030209 endocrinology & metabolismHealth benefitslivermyokinelcsh:Physiologyconjugated linoleic acid03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicinePhysiology (medical)MyokinemedicineFatty acid synthesisfatty acid liver exercise myokine conjugated linoleic acidchemistry.chemical_classificationlcsh:QP1-981exerciseintegumentary systemfood and beveragesFatty acidBrief Research Report030104 developmental biologyEndocrinologyEnzymeLiver metabolismchemistrylipids (amino acids peptides and proteins)Composition (visual arts)fatty acidFrontiers in Physiology
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[The activation of methionine for transmethylation in regenerating rat liver and hepatoma].

1958

The activity of methionine-activating enzyme has been measured in normal and regenerating rat liver and in hepatoma cells.

Cancer Researchmedicine.medical_specialtyCarcinoma HepatocellularMethionine metabolismBiochemical Phenomenachemistry.chemical_compoundMethionineInternal medicinemedicineAnimalschemistry.chemical_classificationMethionineHematologyChemistryLiver NeoplasmsGeneral Medicinedigestive system diseasesRatsLiver metabolismEnzymeOncologyBiochemistryLiverRat liverHepatoma cellTransmethylationZeitschrift fur Krebsforschung
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Experimentelle Untersuchung über die Harnstoffsynthese in der Leber bei entzündlichen und traumatischen Kniegelenksschäden beim Kaninchen

1961

Im Tierexperiment findet man bei entzundlichen und traumatischen Gelenkerkrankungen eine Steigerung der Harnstoffsynthese in der Leber. Trotz der morphologisch sehr differenten und in ihrer Massivitat wechselnden ortlichen Schadigung des Stratum synoviale ist die beobachtete Steigerung der Harnstoffsynthese in der Leber fast gleich. Die morphologisch fasbaren Leberveranderungen sind sparlich und lassen keine bindenden Ruckschlusse auf den Grad der Aktivitat der Leberzelle bezuglich der Harnstoffsynthese zu. Es wird auf Grund der Untersuchungsergebnisse der Schlus gezogen, das die ortlich induzierte Entzundung primar lediglich auslosende Ursache fur die Steigerung der Leberzellaktivitat ist,…

Gynecologymedicine.medical_specialtyLiver metabolismChemistrymedicineGeneral MedicineUrea metabolismZeitschrift für Die Gesamte Experimentelle Medizin
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Putative role of cationic amino acid transporter‐3 in murine liver metabolism

2015

HepatologybiologyChemistryLipid metabolismFastingMetabolismLipid MetabolismMolecular biologyFatty LiverLiver metabolismLiverBiochemistryStarvationbiology.proteinAmino Acid Transport Systems BasicAnimalsHumansMurine liverCATIONIC AMINO ACID TRANSPORTER 3Hepatology
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Darunavir en situaciones especiales

2016

Microbiology (medical)Liver metabolismTratamiento farmacologicobusiness.industryCobicistatmedicineHIV Protease InhibitorRitonavirPharmacologybusinessDarunavirmedicine.drugEnfermedades Infecciosas y Microbiología Clínica
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Bestimmung von Glykolyse-Metaboliten in isolierten Zellkernen

1958

Isolated rat liver nuclei have been analyzed for the intranuclear concentration of 8 glycolytic metabolites, and in addition for the 3 adenine nucleotides, and for malate. All these substrates are to be found in nuclei in a range of concentration comparable to that in the whole tissue. The consequences of these findings with respect to the definite establishment of glycolysis in isolated nuclei, as well as for the intranuclear formation of energy-rich phosphate bonds, are discussed.

PharmacologyCell BiologyCarbohydrate metabolismPhosphateCellular and Molecular Neurosciencechemistry.chemical_compoundCell nucleusLiver metabolismmedicine.anatomical_structurechemistryBiochemistryAdenine nucleotideRat livermedicineMolecular MedicineGlycolysisMolecular BiologyIsolated cellExperientia
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Biological properties of extracellular vesicles and their physiological functions

2015

The authors wish to thank Dr R Simpson and Dr D Taylor for critical reading of the manuscript and acknowledge the Horizon 2020 European Cooperation in Science and Technology programme and its support of our European Network on Microvesicles and Exosomes in Health & Disease (ME-HaD; BM1202 www.cost.eu/COST_Actions/bmbs/Actions/BM1202). In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity to transfer proteins, lipids and nucleic acids, thereby influencing various physiological and pathological functions of both recipient and parent cells. While intensive invest…

ProteomicsCellular distributionMATURE DENDRITIC CELLSReviewReview ArticleUrineEmbryo developmentMonocyteProtein processingVascular biologyFecesVesícules seminalsSYNCYTIOTROPHOBLAST MICROVILLOUS MEMBRANESCell selectionPregnancyT lymphocyteBileCELL-DERIVED EXOSOMESBiogenesisLung lavageUterus fluidInnate immunityMale genital systemlcsh:CytologyMicrovesicleOUTER-MEMBRANE VESICLESBlood clottingprokaryoteEukaryotaExtracellular vesicleRNA analysisCell biologyBloodCerebrospinal fluidLiver metabolismmicrovesicleMorphogenHumanNervous systemCell signalingBreast milkNatural killer cellFisiologiaExtracellular vesiclesExosomelcsh:QH573-671SalivaBiologyBiology and Life SciencesDNAPlantRNA transportCell functionMacrophageMolecular biologyPhysiologyMedizinProteomicsFACTOR PATHWAY INHIBITOReukaryoteProtein glycosylationExtracellular spaceTissue repairEspai extracel·lularReticulocyteSeminal plasmaMesenchymal stem cellAntigen presenting cellSeminal vesiclesNose mucusBiofilmNeutrophilMicroRNAPLANT-MICROBE INTERACTIONSLipidAmnion fluidProkaryotamicroparticleCell interactionCell transporteukaryote exosome extracellular vesicle microparticle microvesicle physiology prokaryoteBone mineralizationMicroorganismHistologyAdaptive immunityMembrane vesicleComputational biologyMembrane receptorBiologyStressCell communicationMast cellMESENCHYMAL STEM-CELLSHUMAN ENDOTHELIAL-CELLSexosomeCytokineSynovial fluidCell BiologyNonhumanIMMUNE-MODULATORY FEATURESReview articleDNA contentphysiologyRNAINTESTINAL EPITHELIAL-CELLSextracellular vesicleBody fluidLectinBiogenesis
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Die Beeinflussung der Harnstoffsynthese in der Leber durch lokale Gewebssch�den beim Kaninchen

1961

Es wird uber in-vitro-Bestimmungen der Harnstoffsynthese der Lebern von Kaninchen mit einer Crotonolentzundung und einer bakteriellen Entzundung des Kniegelenks und einer mechanischen Kniegelenksentzundung berichtet. Es findet sich eine deutliche Zunahme der Harnstoffbildung gegenuber den bei den Kontrolltieren festgestellten Werten. Die Ergebnisse werden hinsichtlich inrer Bedeutung fur die Pathogenese extrarenaler Azotamien diskutiert.

chemistry.chemical_compoundLiver metabolismChemistryDrug DiscoveryUreaMolecular MedicineGeneral MedicineMolecular biologyUrea metabolismGenetics (clinical)Klinische Wochenschrift
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SIRT1 regulation of insulin-signalling pathways in liver, white adipose tissue and pancreas during fasting or calorie restriction

2007

In an excellent review by Yang et al.[1], published in issue 5 of Trends in Endocrinology and Metabolism, the involvement of the human sirtuin SIRT1 in nutrient-sensing and insulin-signalling pathways is explained. The regulation of SIRT1 with fasting in liver, pancreas and white adipose tissue is illustrated (see Figure 2 of Yang et al.). We consider that the depiction in the article by Yang et al. could be misleading for the reader, and we propose a modified version (Figure 1).

medicine.medical_specialtybiologybusiness.industrySirtuin 1Endocrinology Diabetes and MetabolismCalorie restrictionAdipose tissueWhite adipose tissuehumanitiesEndocrinologyEndocrinologymedicine.anatomical_structureLiver metabolismInternal medicineSirtuinmedicinebiology.proteinbusinessPancreashuman activitiesInsulin signallingTrends in Endocrinology & Metabolism
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